DNBC - Danish National Birth Cohort / Better Health in Generations
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Exposures in the period from conception to early childhood - including fetal growth, cell division, and organ functioning - may have long-lasting impact on health and disease susceptibility. To investigate these issues the Danish National Birth Cohort (Better health in generations) was established. The Danish National Birth Cohort is a large cohort of pregnant women with long-term follow-up of the offspring was the obvious choice because many of the exposures of interest cannot be reconstructed with sufficient validity back in time. The study needed to be large, and the aim was to recruit 100,000 women early in pregnancy, and to continue follow-up for decades.
Visit DNBC
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Overview
- Acronym
- DNBC
- Start Year
- 1996
- Follow Up Is Ongoing
- Year of Most Recent Data Collection
- 2014
- New Data Collection planned?
- No
Access
Access to external researchers or third parties provided or foreseen.
- Data (questionnaire-derived, measured...)
- Biosamples
- Other access
Study Design
- Study design
- Cohort
- Number of Data Collection Events
- 5
- Number of very preterm (VPT) and/or very low birthweight (VLBW) births included in cohort (live & still births)
- 96834
- Supplementary information about number of participants
- Number of live born children 96834.
Marker Paper
Olsen J, Melbye M, Olsen SF, Sorensen TI, Aaby P, Andersen AM, Taxbol D, Hansen KD, Juhl M, Schow TB, Sorensen HT, Andresen J, Mortensen EL, Olesen AW, Sondergaard C. The Danish National Birth Cohort--its background, structure and aim. Scand J Public Health. 2001;29(4):300-7.
PUBMED 11775787
Timeline
DNBC Cohort
A population based pregnancy cohort following up mothers and infants. Participating infants were born in 1996-2002. The cohort includes births at all gestational ages (it is not specifically a preterm birth cohort), however, an index group can be defined based on gestational age or birthweight.
Selection Criteria
- Countries
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- Denmark
- Geographical Area
- All counties in Denmark
- VPT/VLBW Group Inclusion Criteria
- As DNBC is a pregnancy and child cohort there is no predefined index or control group. However, it is possible to define an index group (e.g. based on gestational age and/or birthweight).
- Control Group Inclusion Criteria
- As DNBC is a pregnancy and child cohort there is no predefined index or control group. However, it is possible to define an index group (e.g. based on gestational age and/or birthweight).
- VPT/VLBW Group Exclusion Criteria
- Women who could not speak Danish well enough to participate in a telephone interview.
- Control Group Exclusion Criteria
- Women who could not speak Danish well enough to participate in a telephone interview.
Data Collection Events
| # | Name | Description | Start | End |
|---|---|---|---|---|
| 0 |
Perinatal Assessment
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During gestational weeks 12 and 30, the mothers were interviewed by telephone about their obstetric history and fertility treatment, general health, health during pregnancy, antenatal ... | 1996 | 2002-10 |
| 1 |
6 Month Follow Up
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At 6 months, the mothers completed a telephone interview about the final part of pregnancy (after 30 weeks) and the first 6 months of the infant's life. Data were linked to the National Birth ... | 1996 | 2002 |
| 2 |
18 Month Follow Up
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When the child was 18 months old, a phone interview with the mother was conducted to collect data about the period from 6 to 18 months of age including details of pregnancies and births since the ... | 1997 | 2003 |
| 3 |
7 Year Follow Up
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At 7 years of age, mothers completed a paper or online questionnaire about the child including details of motor skills, handedness, development, language development, diet, vitamins and ... | 2005-11 | 2010-07 |
| 4 |
11 Year Follow Up
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At 11 years of age, parents and participants completed online questionnaires. The parental questionnaire included questions on the child's diet, vitamins and supplements, sun exposure and use of ... | 2010-07 | 2014-08 |