Individual Study / UA_EPIBEL

UA_EPIBEL - Antwerp University EPIBEL

Networks -
Datasets -
Variables -


Investigators Contacts
  • Herbert Roeyers
    University of Ghent
  • Piet Vanhaesebrouck
    emer. University Hospital Ghent
  • Liedewij Verhaeghe
    University of Ghent
  • Jo Lebeer
    University of Antwerp
  • Patrick Van Reempts
    emer. Antwerp University Hospital
  • Isabel De Groote
    University Hospital Ghent
  • Iemke Sarrechia
    Universiteit Antwerpen


Start Year
End Year
Follow Up Is Ongoing
Year of Most Recent Data Collection
New Data Collection planned?
This study was supported by the Belgian Ministry of Health; the Foundation Marguerite Marie Delacroix; the Research Foundation Flanders (FWO)


Access to external researchers or third parties provided or foreseen.

Data (questionnaire-derived, measured...)
Other access

Supplementary Information

Perinatal data for surviving and non-surviving infants in Belgium [N=441,excluding late abortions, N=84], Follow up data (3y &11-15y) only for the Flemish region.

Study Design

Study design
Number of Data Collection Events
Number of very preterm (VPT) and/or very low birthweight (VLBW) births included in cohort (live & still births)
Supplementary information about number of participants
525 births were recorded. A total of 350 (66.6%) infants died. A total of 222 (42.3%) nonsurviving infants were not admitted to the NICU, 203 (91%) of whom died after the onset of labor or immediately at birth and 19 (9%) infants in the delivery room after active resuscitation. Of the 303 neonates who were admitted to the NICU, 42.2% died before discharge and 175 (57.8%) were still alive at discharge from hospital. Perinatal dataset N=441 (excluding late abortions, N=84) FU at 3y Flemish participants N=77 FU at 11y-15y Flemish participants N= 53

Marker Paper

Vanhaesebrouck P, Allegaert K, Bottu J, Debauche C, Devlieger H, Docx M, François A, Haumont D, Lombet J, Rigo J, Smets K, Vanherreweghe I, Van Overmeire B, Van Reempts P;  Extremely Preterm Infants in Belgium Study Group. (2004). The EPIBEL study: outcomes to discharge from hospital for extremely preterm infants in Belgium. Pediatrics 114: 663–75

PUBMED 15342837
Additional Publications
  • De Groote I, Vanhaesebrouck P, Bruneel E, Dom L, Durein I, Hasaerts D, Laroche S, Oostra A, Ortibus E, Roeyers H, van Mol C; Extremely Preterm Infants in Belgium (EPIBEL) Study Group. (2007) OBSTETRICS AND GYNECOLOGY. 110(4). p.855-864
  • Verhaeghe, Liedewij, Dereu, M., Warreyn, P., De Groote, I., Vanhaesebrouck, P., & Roeyers, H. (2016). Extremely preterm born children at very high risk for developing autism spectrum disorder. CHILD PSYCHIATRY & HUMAN DEVELOPMENT, 47(5), 729–739



Selection Criteria
  • Belgium
Geographical Area
All of Belgium
VPT/VLBW Group Inclusion Criteria
All inborn births between 22+0 and 26 + 6 completed weeks of gestation.
Control Group Inclusion Criteria
VPT/VLBW Group Exclusion Criteria
Outborn infants (16% of EPT infants admitted) are not included.
Control Group Exclusion Criteria
Data Collection Events
# Name Description Start End
0 Perinatal Assessment 1999 2000
1 3 year Follow Up 2002 2004
2 11-15 Year Follow Up 2011 2014