Individual Study / EPICure

EPICure - EPICure

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Investigators Contacts
  • Dr Yanyan Ni
    University College London


Start Year
Follow Up Is Ongoing
Year of Most Recent Data Collection
New Data Collection planned?


Access to external researchers or third parties neither provided nor foreseen.

Study Design

Study design
Number of Data Collection Events
Number of very preterm (VPT) and/or very low birthweight (VLBW) births included in cohort (live & still births)
Supplementary information about number of participants
306 long term survivors

Marker Paper

Costeloe K, Hennessy E, Gibson AT, Marlow N, Wilkinson AR. The EPICure study: outcomes to discharge from hospital for infants born at the threshold of viability. Pediatrics. 2000;106:659-71.

Two year data:
Wood NS, Marlow N, Costeloe K, et al. Neurologic and developmental disability after extremely preterm birth. New England Journal of Medicine 2000;343(6):378-84. doi: 10.1056/NEJM200008103430601

PUBMED 11015506


EPICure Cohort

Selection Criteria
  • United Kingdom
  • Ireland
Geographical Area
All of United Kingdom and Repulic of Ireland
VPT/VLBW Group Inclusion Criteria
Birth at or before 25+6 weeks of gestation.
Control Group Inclusion Criteria
Controls were recruited at the 6 year follow-up by identifying classmates of index children in mainstream school who were born at term (37+0 or more weeks of gestation). Controls were used in subsequent assessments.
VPT/VLBW Group Exclusion Criteria
Control Group Exclusion Criteria
Birth before 37+0 weeks gestational age.
Supplementary Information
Control group included for 6, 11, 19 year follow up. Where possible the same control child was used at 6 and 11 year follow ups, if not a new child was selected.
Data Collection Events
# Name Description Start End
0 Perinatal Assessment 1995 1995
1 2.5 Year Follow Up 1998 1999
2 6 Year Follow Up 2001 2002
3 11 Year Follow Up 2005 2007
4 19 Year Follow Up 2014 2015