EXPRESS - Extremely Preterm Infants in Sweden Study
The primary aims of the EXPRESS study are to determine perinatal and infant mortality and morbidity by gestational age in weeks, to identify risk factors for adverse outcomes, and to evaluate long-term health among infants born EPT.
- Start Year
- Follow Up Is Ongoing
- Year of Most Recent Data Collection
- New Data Collection planned?
- Data (questionnaire-derived, measured...)
- Other access
A 4th collection event is ongoing.
- Study design
- Number of Data Collection Events
- Number of very preterm (VPT) and/or very low birthweight (VLBW) births included in cohort (live & still births)
Fellman V, Hellstrom-Westas L, Norman M, Westgren M, Kallen K, Lagercrantz H, Marsal K, Serenius F, Wennergren M. One-year survival of extremely preterm infants after active perinatal care in Sweden. JAMA. 2009;301(21):2225-33.
Collaborators: Blennow M, Ewald U, Fritz T, Holmgren PA, Jeppsson A, Lindberg E, Lundqvist A, Lindeberg SN, Olhager E, Ostlund I, Simic M, Sjörs G, Stigson L, Fellman V, Hellström-Westas L, Norman M, Westgren M, Holmström G, Laurini R, Stjernqvist K, Källén K, Lagercrantz H, Marsál K, Serenius F, Wennergren M, Nilstun T, Olausson PO, Strömberg B. JAMA 2009;301(21):2225-33.
- Geographical Area
- All of Sweden
- VPT/VLBW Group Inclusion Criteria
- The study population comprised all live-born (gestational age <27+0 weeks) and stillborn infants (gestational age 22+0 weeks – 26+6 weeks) delivered extremely preterm in Sweden from April 1, 2004, to March 31, 2007.
- Control Group Inclusion Criteria
- Selection criteria for controls were singleton at-term birth with a 5-minute Apgar score greater than 3 with matching of control participants for place of living, sex, day of birth, and maternal country of birth.
- VPT/VLBW Group Exclusion Criteria
- Women delivering extremely preterm but not residing in Sweden in study period. Terminations of pregnancy and infants born outside of Sweden and transferred to Sweden for neonatal care were also excluded.
- Control Group Exclusion Criteria
Data Collection Events
||Data were collected prospectively by local hospital staff and cross-linked with the National Medical Birth Registry to ensure the accuracy of the information captured. Data on mothers and still ...||2004||2007|
2.5 year Follow Up
||Participants were assessed at 30 months by a psychologist and pediatrician or pediatric neurologist.
The Bayley Scales of Infant and Toddler Development – Third Edition (Bayley-III) ...
6.5 year Follow Up
||Participants were assessed at 6.5 years of age. Cognitive function was assessed with the Wechsler Intelligence Scale for Children, Fourth Edition (WISC-IV). A neuropediatric assessment was ...||2010||2014|