Individual Study / POPS

POPS - Project On Preterm and Small for gestational age infants

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Networks -
Datasets -
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Investigators Contacts
  • Sylvia van der Pal
  • Sylvia van der Pal


Start Year
Follow Up Is Ongoing
Year of Most Recent Data Collection
New Data Collection planned?


Access to external researchers or third parties provided or foreseen.

Data (questionnaire-derived, measured...)
Other access

Study Design

Study design
Number of Data Collection Events
Number of very preterm (VPT) and/or very low birthweight (VLBW) births included in cohort (live & still births)

Marker Paper

Van der Pal-de Bruin KM, van der Pal SM, Verloove-Vanhorick SP, Walther FJ. Profiling the preterm or VLBW born adolescent; implications of the Dutch POPS cohort follow-up studies. Early Hum Dev. 2015;91(2):97-102.

1. Verloove-Vanhorick SP, Verwey RA, Brand R, Bennebroek Gravenhorst J, Keirse MJNC, Ruys JH. Neonatal mortality in relation to gestational age and birth weight. Results of a national survey of preterm and very-low-birth weight infants in the Netherlands. Lancet 1986;55–57.
2. Hille ET, Weisglas-Kuperus N, van Goudoever JB, Jacobusse GW, Ens-Dokkum MH, de Groot L, et al. Functional outcomes and participation in young adulthood for very preterm and very low birth weight infants: the Dutch project on preterm and small for gestational age infants at 19 years of age. Pediatrics 2007;120(3):e587–95.
3. Hille ETM, Elbertse MD, Bennebroek Gravenhorst J, Brand R, Verloove-Vanhorick SP. Nonresponse bias in a follow-up study of 19-year-old adolescents born as preterm infants. Pediatrics 2005;116(5):662–6.
4. Hille ETM, den Ouden AL, Stuifbergen MC, Verrips GHW, Vogels AGC, Brand R, et al. Is attribution bias a problem in neonatal follow-up? Early HumDev 2005;81:901–8.
5. van Buuren S. Flexible imputation of missing data. Boca Raton: Chapman & Hall/CRC Press; 2012.
6. Rubin DB. Multiple imputation for nonresponse in surveys. New York: JohnWiley & sons; 1987.
7. Van Lunenburg A, van der Pal SM, van Dommelen P, van der Pal-de Bruin KM, Bennebroek Gravenhorst J, Verrips GH. Changes in quality of life into adulthood after very preterm birth and/or very low birth weight in the Netherlands. Health Qual Life Outcomes. 2013:26;11:51.
8. Van Gendt AW, van der Pal SM, Hermes W, Walther FJ, van der Pal-de Bruin KM, de Groot CJ. Reproductive outcomes of women and men born very preterm and/or with a very low birth weight in 1983: a longitudinal cohort study in the Netherlands. Eur J Pediatr. 2015;174(6):819-25.

PUBMED 25590235


POPS Cohort

Selection Criteria
  • Netherlands
Geographical Area
All of the Netherlands
VPT/VLBW Group Inclusion Criteria
Very preterm (<32 completed weeks of gestation) and/or very low birth weight (<1500 g) infants.
Control Group Inclusion Criteria
VPT/VLBW Group Exclusion Criteria
Control Group Exclusion Criteria
Data Collection Events
# Name Description Start End
0 Perinatal Assessment 1983 1983
1 Discharge to 1 Year Follow Up 1983 1984
2 2 Year Follow Up 1985 1985
3 5 Year Follow Up 1988 1988
4 9 Year Follow Up 1992 1992
5 10 Year Follow Up 1993 1993
6 11 Year Follow Up 1994 1994
7 14 Year Follow Up 1997 1997
8 19 Year Follow Up 2002 2003
9 28 Year Follow Up 2011 2011
10 35 Year Follow Up 2018